Kisspeptin
đź“ť LAB NOTES
Kisspeptin is a research peptide studied for its central role in reproductive hormone signaling and regulation of the hypothalamic-pituitary-gonadal (HPG) axis. Research has explored its influence on gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), and follicle-stimulating hormone (FSH), making it of particular interest in studies involving fertility, reproductive function, hormone signaling, and endocrine regulation.
TARGETED RESEARCH USE
Reproductive hormone signaling, fertility-related pathways, HPG-axis regulation, GnRH activity, gonadotropin secretion, LH and FSH response, reproductive endocrinology, and related hormonal mechanisms.
RESEARCH REFERENCES
Oakley AE, Clifton DK, Steiner RA. Kisspeptin Signaling in the Brain. Endocrine Reviews. 2009;30(6):713–743.View Study on PubMed
Pinilla L, Aguilar E, Dieguez C, Millar RP, Tena-Sempere M. Kisspeptins and Reproduction: Physiological Roles and Regulatory Mechanisms. Physiological Reviews. 2012;92(3):1235–1316.View Study on PubMed
Dhillo WS, Chaudhri OB, Patterson M, et al. Kisspeptin-54 Stimulates the Hypothalamic-Pituitary Gonadal Axis in Human Males. Journal of Clinical Endocrinology & Metabolism. 2005;90(12):6609–6615.View Study on PubMed
Jayasena CN, Nijher GMK, Chaudhri OB, et al. Subcutaneous Injection of Kisspeptin-54 Acutely Stimulates Gonadotropin Secretion in Women With Hypothalamic Amenorrhea but Chronic Administration Causes Tachyphylaxis. Clinical Endocrinology. 2009;70(5):785–790.View Study on PubMed
⚠️ FOR RESEARCH USE ONLY — NOT FOR HUMAN OR ANIMAL USE
This research compound is supplied as a lyophilized powder in a sealed 3 mL vial to support stability and proper laboratory handling. Certificate of Analysis (COA) available for verification. Reconstitution is required prior to research use.