SEMAX
đź“ť LAB NOTES
Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4–10) and studied for its potential influence on neurological signaling, cognitive processes, neuroplasticity, and neuroprotective mechanisms. Research has explored its relationship with brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), memory and learning pathways, attention, cellular responses to neurological stress, and gene expression within the nervous system.
TARGETED RESEARCH USE
Cognitive signaling, memory and learning pathways, attention and focus mechanisms, neuroplasticity, BDNF and neurotrophin signaling, neuroprotective processes, neurological stress-response pathways, gene expression, and nervous-system research.
RESEARCH REFERENCES
Dolotov OV, Karpenko EA, Inozemtseva LS, et al. Semax, an Analog of ACTH(4–10) With Cognitive Effects, Regulates BDNF and trkB Expression in the Rat Hippocampus. Brain Research. 2006;1117(1):54–60. — View Study on PubMed
Dolotov OV, et al. Semax, an Analogue of Adrenocorticotropin (4–10), Binds Specifically and Increases BDNF Levels in Rat Basal Forebrain. Neuroscience Letters. 2006. — View Study on PubMed
Medvedeva EV, Dmitrieva VG, Povarova OV, et al. The Peptide Semax Affects the Expression of Genes Related to the Immune and Vascular Systems in Rat Brain Focal Ischemia: Genome-Wide Transcriptional Analysis. BMC Genomics. 2014;15:228. — View Full Study on PubMed Central
Shadrina MI, Kolomin TA, Agapova TY, et al. Comparison of the Temporary Dynamics of NGF and BDNF Gene Expression in Rat Hippocampus, Frontal Cortex, and Retina Under Semax Action. Journal of Molecular Neuroscience. 2010;41:30–35. — View Study on PubMed
⚠️ FOR RESEARCH USE ONLY — NOT FOR HUMAN OR ANIMAL USE
This research compound is supplied as a lyophilized powder in a sealed 3 mL vial to support stability and proper laboratory handling. Certificate of Analysis (COA) available for verification. Reconstitution is required prior to research use.