PT-141
đź“ťLAB NOTES
PT-141, also known as Bremelanotide, is a synthetic research peptide and melanocortin receptor agonist studied for its effects on neurological pathways involved in sexual desire, arousal, and sexual function. Unlike compounds that act primarily through vascular pathways, PT-141 has been researched for its activity within the central nervous system and its influence on melanocortin signaling.
TARGETED RESEARCH USE
Sexual desire and libido, arousal pathways, melanocortin receptor signaling, female sexual function, erectile response, and neurological mechanisms associated with sexual behavior.
RESEARCH REFERENCES
Molinoff PB, Shadiack AM, Earle D, Diamond LE, Quon CY. PT-141: A Melanocortin Agonist for the Treatment of Sexual Dysfunction. Annals of the New York Academy of Sciences. 2003;994:96–102.View Study on PubMed
Diamond LE, Earle DC, Heiman JR, Rosen RC, Perelman MA, Harning R. An Effect on the Subjective Sexual Response in Premenopausal Women with Sexual Arousal Disorder by Bremelanotide (PT-141), a Melanocortin Receptor Agonist. Journal of Sexual Medicine. 2006;3(4):628–638.View Study on PubMed
Kingsberg SA, Clayton AH, Portman D, et al. Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials. Obstetrics & Gynecology. 2019;134(5):899–908.View Study on PubMed
Diamond LE, Earle DC, Rosen RC, Willett MS, Molinoff PB. Double-Blind, Placebo-Controlled Evaluation of the Safety, Pharmacokinetic Properties and Pharmacodynamic Effects of Intranasal PT-141, a Melanocortin Receptor Agonist, in Healthy Males and Patients with Mild-to-Moderate Erectile Dysfunction. International Journal of Impotence Research. 2004;16(1):51–59.View Study on PubMed
⚠️ FOR RESEARCH USE ONLY — NOT FOR HUMAN OR ANIMAL USE
This research compound is supplied as a lyophilized powder in a sealed 3 mL vial to support stability and proper laboratory handling. Certificate of Analysis (COA) available for verification. Reconstitution is required prior to research use.