KPV

📝 LAB NOTES

KPV (Lysine-Proline-Valine) is a naturally occurring tripeptide fragment derived from α-melanocyte-stimulating hormone (α-MSH). It is studied for its potential role in inflammation-related signaling, immune response modulation, intestinal barrier function, and cellular processes associated with tissue protection. Research interest has particularly focused on inflammatory pathways involving the gastrointestinal tract and skin.

TARGETED RESEARCH USE

Inflammation-related signaling, immune response pathways, intestinal and gut barrier function, gastrointestinal research, skin-related inflammatory processes, cellular protection, and tissue-response mechanisms.

RESEARCH REFERENCES

• Kannengiesser K, Maaser C, Heidemann J, Luegering A, Ross M, Brzoska T, Bohm M, Luger TA, Domschke W, Kucharzik T. Melanocortin-Derived Tripeptide KPV Has Anti-Inflammatory Potential in Murine Models of Inflammatory Bowel Disease. Inflammatory Bowel Diseases. 2008;14(3):324–331.View Study on PubMed

• Dalmasso G, Charrier-Hisamuddin L, Thu Nguyen HT, Yan Y, Sitaraman S, Merlin D. PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation. Gastroenterology. 2008;134(1):166–178.View Study on PubMed

• Mastrofrancesco A, Kokot A, Eberle A, Gibbons NCJ, Schallreuter KU, Strozyk E, Picardo M, Zouboulis CC, Luger TA, Bohm M. KPV and Related Melanocortin Peptides in Cutaneous Inflammation and Cellular Responses.Explore Related KPV Research on PubMed

⚠️ FOR RESEARCH USE ONLY — NOT FOR HUMAN OR ANIMAL USE

This research compound is supplied as a lyophilized powder in a sealed 3 mL vial to support stability and proper laboratory handling. Certificate of Analysis (COA) available for verification. Reconstitution is required prior to research use.