Ipamorelin
đź“ť LAB NOTES
Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue studied for its activity at the growth hormone secretagogue receptor (GHS-R1a), also known as the ghrelin receptor. Research has explored its ability to stimulate growth hormone (GH) release and its potential influence on endocrine signaling, GH-related pathways, body composition, bone metabolism, tissue recovery, and other biological processes associated with the growth hormone axis.
Ipamorelin is of particular research interest because early preclinical studies characterized it as a selective growth hormone secretagogue with less stimulation of adrenocorticotropic hormone (ACTH) and cortisol pathways than some earlier growth hormone-releasing peptides under the experimental conditions studied.
TARGETED RESEARCH USE
Growth hormone secretion, GHS-R1a and ghrelin receptor signaling, endocrine regulation, GH and IGF-1-related pathways, pulsatile growth hormone research, body composition, bone metabolism, muscle-related biological processes, tissue recovery pathways, protein metabolism, and age-related changes in growth hormone signaling.
RESEARCH REFERENCES
Raun K, Hansen BS, Johansen NL, et al. Ipamorelin, the First Selective Growth Hormone Secretagogue. European Journal of Endocrinology. 1998;139(5):552–561. — View Study on PubMed
Johansen PB, Nowak J, Skjaerbaek C, Flyvbjerg A, Andreassen TT, Wilken M, Orskov H. Ipamorelin, a New Growth-Hormone-Releasing Peptide, Induces Longitudinal Bone Growth in Rats. Growth Hormone & IGF Research. 1999;9(2):106–113. — View Study on PubMed
Raun K, Hansen BS, Johansen NL, et al. Research into the pharmacological profile and selectivity of Ipamorelin has examined its GH-releasing activity and effects on related endocrine pathways. — Explore Ipamorelin Research on PubMed
⚠️ FOR RESEARCH USE ONLY — NOT FOR HUMAN OR ANIMAL USE
This research compound is supplied as a lyophilized powder in a sealed 3 mL vial to support stability and proper laboratory handling. Certificate of Analysis (COA) available for verification. Reconstitution is required prior to research use.