Cagrilintide

📝 LAB NOTES

Cagrilintide is a long-acting acylated amylin analog studied for its activity within metabolic and appetite-regulation pathways. Research has focused on its effects on satiety signaling, food intake, body-weight regulation, gastric emptying, and energy balance. As an amylin analog, cagrilintide is of particular research interest for its activity within central and peripheral pathways involved in metabolic regulation.

TARGETED RESEARCH USE

Amylin receptor signaling, appetite and satiety pathways, food-intake regulation, body-weight regulation, energy balance, gastric emptying, metabolic signaling, and obesity-related research.

RESEARCH REFERENCES

• Lau DCW, Erichsen L, Francisco AM, et al. Once-Weekly Cagrilintide for Weight Management in People With Overweight and Obesity: A Multicentre, Randomised, Double-Blind, Placebo-Controlled and Active-Controlled, Dose-Finding Phase 2 Trial. The Lancet. 2021;398(10317):2160–2172. View Study on PubMed: Once-weekly cagrilintide Phase 2 study

• Enebo LB, Berthelsen KK, Kankam M, et al. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Concomitant Administration of Multiple Doses of Cagrilintide With Semaglutide 2.4 mg for Weight Management: A Randomised, Controlled, Phase 1b Trial. The Lancet. 2021;397(10286):1736–1748. View Study on PubMed: Cagrilintide with semaglutide Phase 1b study

• Fletcher MM, Keov P, Truong TT, et al. The Role of Amylin and Its Receptors in the Regulation of Energy Homeostasis. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 2021;320(4)–R518. View Study on PubMed: Amylin and energy homeostasis research

  
  

⚠️ FOR RESEARCH USE ONLY — NOT FOR HUMAN OR ANIMAL USE

This research compound is supplied as a lyophilized powder in a sealed 3 mL vial to support stability and proper laboratory handling. Certificate of Analysis (COA) available for verification. Reconstitution is required prior to research use.